{"id":59,"date":"2022-02-07T01:25:24","date_gmt":"2022-02-07T01:25:24","guid":{"rendered":"http:\/\/8.136.84.94\/wp-blog\/?page_id=59"},"modified":"2023-09-22T06:24:43","modified_gmt":"2023-09-22T06:24:43","slug":"etaluma-ls720","status":"publish","type":"page","link":"http:\/\/8.136.84.94\/wp-blog\/index.php\/etaluma-ls720\/","title":{"rendered":"Etaluma LS720 \u5168\u81ea\u52a8\u6d3b\u7ec6\u80de\u76d1\u63a7\u7cfb\u7edf"},"content":{"rendered":"\n
\"\"<\/figure>\n\n\n\n

\u6d3b\u7ec6\u80de\u6210\u50cf\u89c2\u5bdf\u7684\u6709\u529b\u5de5\u5177<\/strong><\/p>\n\n\n\n

\u7279\u6b8a\u7684\u5149\u8def\u8bbe\u8ba1\uff0c\u5bc6\u5c01\u7684\u4f53\u7cfb\u4f7fEtaluma\u65e0\u9700\u5916\u914d\u57f9\u517b\u88c5\u7f6e\uff0c\u800c\u76f4\u63a5\u653e\u7f6e\u5728\u5e38\u89c4\u4e8c\u6c27\u5316\u78b3\u57f9\u517b\u7bb1\u3001\u4e09\u6c14\u57f9\u517b\u7bb1\u3001\u538c\u6c27\u7bb1\u30014\u2103\u51b0\u7bb1\u3001\u8d85\u51c0\u5de5\u4f5c\u53f0\u7b49\uff0c\u5bf9\u5404\u7c7b\u52a8\u690d\u7269\u3001\u5fae\u751f\u7269\u7684\u6d3b\u7ec6\u80de\u6216\u7ec4\u7ec7\u76f4\u63a5\u89c2\u5bdf\u6210\u50cf\uff0c\u7a33\u5b9a\u7684\u57f9\u517b\u73af\u5883\u53ef\u4fdd\u6301\u6d3b\u4f53\u6837\u672c\u8fde\u7eed\u91c7\u96c6\u957f\u8fbe\u6570\u6708\uff1b\u53ef\u5b9e\u73b0\u771f\u6b63\u76842D\/3D\u6d3b\u7ec6\u80de\u6837\u672c\u9ad8\u901a\u91cf\u5b9e\u65f6\u89c2\u5bdf\u3002<\/p>\n\n\n\n

\n
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\u5f00\u653e\u6027\u5e73\u53f0<\/p>\n\n\n\n

\u5e73\u53f0\u5f00\u653e\u5f0f\u8bbe\u8ba1\uff0c\u7075\u6d3b\u7a33\u5b9a\u7684\u64cd\u4f5c\u5e73\u53f0\u53ef\u4ee5\u642d\u8f7d\u663e\u5fae\u6ce8\u5c04\u4eea\uff0c\u5355\u7ec6\u80de\u91c7\u96c6\u7cfb\u7edf\uff0c\u819c\u7247\u94b3\u7b49\u8fdb\u884c\u591a\u91cd\u5e94\u7528\u7ec4\u5408\uff0c\u5b9e\u73b0\u81ea\u52a8\u5316\u76d1\u63a7\u4e0e\u663e\u5fae\u6ce8\u5c04\uff0c\u5355\u7ec6\u80de\u6355\u83b7\u7b49\u540c\u65f6\u64cd\u4f5c\u3002<\/p>\n\n\n\n

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\u517c\u5bb9\u5e38\u89c4\u6837\u54c1\u5bb9\u5668<\/p>\n\n\n\n

\u517c\u5bb9\u5e38\u89c46-384\u5b54\u677f\u3001\u8f7d\u73bb\u7247\u300135mm\u57f9\u517b\u76bf\u300150mm\u57f9\u517b\u76bf\u3001100mm\u57f9\u517b\u76bf\u3001T-25\u6216T-75\u57f9\u517b\u74f6\u3001\u5fae\u6d41\u63a7\u82af\u7247\u7b49\u3002<\/p>\n\n\n\n

\u591a\u79cd\u7269\u955c\u89c4\u683c\u53ef\u9009<\/p>\n\n\n\n

\u65e0\u9650\u8fdc\u6821\u6b63\u3001RWS\u87ba\u7eb9\u3001\u6d3b\u7ec6\u80de\u4e13\u7528\u7684\u957f\u5de5\u4f5c\u8ddd\u79bb\u7269\u955c\uff1b1.25\u00d7-100\u00d7\u7269\u955c\u53ef\u9009\uff0c\u660e\u573a\u3001\u76f8\u5dee\u7269\u955c\u53ef\u9009\uff0c\u65e2\u53ef\u4ee5\u89c2\u5bdf\u7fa4\u4f53\u7ec6\u80de\uff0c\u53c8\u53ef\u5bf9\u4e9a\u7ec6\u80de\u7ed3\u6784\u8fdb\u4e00\u6b65\u89c2\u5bdf\u3002<\/p>\n<\/div>\n<\/div>\n\n\n\n

\n
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\u6210\u50cf\u6a21\u5f0f<\/strong><\/p>\n\n\n\n

\n
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\u52a8\u6001\u5f71\u50cf<\/p>\n\n\n\n

Etaluma\u53ef\u4ee5\u540c\u65f6\u5bf91536\u4e2a\u6837\u672c\u81ea\u52a8\u7684\u91c7\u96c6\uff0c\u6bcf\u4e2a\u6837\u672c\u7684\u65f6\u95f4\u8fde\u7eed\u56fe\u50cf\u53ef\u4ee5\u81ea\u52a8\u5408\u6210\u52a8\u6001\u89c6\u9891\uff1b\u4e14\u6574\u4e2a\u91c7\u96c6\u8fc7\u7a0b\u7ec6\u80de\u6837\u672c\u4e0d\u79bb\u5f00\u539f\u6709\u57f9\u517b\u73af\u5883\uff0c\u5728\u5f3a\u5927\u7684\u805a\u7126\u6a21\u5757\u4e0b\u53ef\u4ee5\u624b\u52a8\u6216\u81ea\u52a8\u62cd\u6444\u77ed\u5219\u51e0\u5206\u949f\uff0c\u957f\u5219\u51e0\u4e2a\u6708\u7684\u6d3b\u7ec6\u80de\u6837\u672c\u3002<\/p>\n\n\n\n

\u5b9a\u70b9\u5f55\u50cf<\/p>\n\n\n\n

\u9499\u79bb\u5b50\u6d41\uff0c\u7ec6\u80de\u6d88\u5316\u7b49\u5b9e\u9a8c\u5b9e\u73b0\u5feb\u901f\u6444\u50cf\u529f\u80fd\uff0c\u4ee530\u6862\/\u79d2\u7684\u6210\u50cf\u901f\u5ea6\u5b9e\u65f6\u6355\u6349\u6837\u672c\u7684\u5feb\u901f\u52a8\u6001\u53d8\u5316\u8fc7\u7a0b\u3002<\/p>\n<\/div>\n\n\n\n

\n
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\u8367\u5149\u6210\u50cf<\/strong><\/p>\n\n\n\n

Etaluma\u5177\u6709\u56fa\u6001\u5149\u5b66\u8bbe\u8ba1\uff0c\u5149\u8def\u957f\u5ea63\u82f1\u5bf8\uff0c\u662f\u5e38\u89c4\u5149\u8def\u957f\u5ea6\u76841\/10\uff0c\u53ef\u5b9e\u73b0\u9ad8\u6548\u5f31\u8367\u5149\u6210\u50cf\u53ca\u8367\u5149\u6807\u8bb0\u6837\u672c\u7684\u957f\u65f6\u95f4\u4f4e\u6f02\u767d\u68c0\u6d4b\uff1b\u7ea2\u7eff\u84dd\u4e09\u8272\u8367\u5149\u901a\u9053\uff0c\u6ee1\u8db3\u591a\u79cd\u8367\u5149\u6837\u672c\u9700\u6c42\u3002<\/p>\n\n\n\n

<\/div>\n\n\n\n

\u660e\u573a\uff0c\u76f8\u5dee\u6210\u50cf<\/strong><\/p>\n\n\n\n

Etaluma\u901a\u8fc7\u5b9e\u65f6\u65e0\u6807\u8bb0\u6210\u50cf\uff0c\u660e\u573a\u6216\u76f8\u5dee\u6a21\u5f0f\u6709\u6548\u63d0\u9ad8\u56fe\u50cf\u5bf9\u6bd4\u5ea6\uff0c\u533a\u5206\u7ec6\u80de\u5185\u7ed3\u6784\u5fae\u5c0f\u5dee\u5f02\uff0c\u5b9e\u73b0\u6837\u54c1\u65e0\u6807\u8bb0\u72b6\u6001\u3002<\/p>\n\n\n\n

<\/div>\n\n\n\n

\u62fc\u63a5\u6210\u50cf<\/strong><\/p>\n\n\n\n

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<\/div>\n\n\n\n

Z-stack\u6210\u50cf<\/strong><\/p>\n\n\n\n

\u6210\u50cf\u7cfb\u7edf\u53ef\u4ee5\u5bf9\u4e0d\u540c\u805a\u7126\u5e73\u9762\u8fdb\u884cZ-stack\u626b\u63cf\uff0c\u6700\u5927\u8986\u76d6\u8303\u56f4\u53ef\u8fbe12000um\uff1b\u4e0d\u4ec5\u53ef\u4ee5\u62cd\u6444\u5230\u540c\u4e00\u89c6\u91ce\u4e0b\u4e0d\u540c\u5c42\u9762\u7684\u56fe\u50cf\uff0c\u8fd8\u80fd\u4ece\u6bcf\u5f20\u56fe\u50cf\u4e2d\u63d0\u53d6\u805a\u7126\u6548\u679c\u50cf\u7d20\u56fe\u7247\uff0c\u751f\u6210Z-max\u56fe\u50cf\u548c\u4e09\u7ef4\u91cd\u6784\u56fe\u50cf\u3002\u9002\u5408\u539a\u7ec4\u7ec7\u6837\u672c\uff0c\u795e\u7ecf\u5143\u53ca\u795e\u7ecf\u7f51\u7edc\u3002<\/p>\n<\/div>\n\n\n\n

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\u5b9e\u9a8c\u65b9\u5411<\/strong><\/p>\n\n\n\n

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\u7ebf\u7c92\u4f53\u635f\u4f24
Transwell\u4fb5\u88ad\u5b9e\u9a8c
DNA\u5408\u6210
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\u5e72\u7ec6\u80de\u7814\u7a76\uff1a<\/strong>
IPSC\u7ec6\u80de\u7cfb\u751f\u4ea7
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\u751f\u7269\u6750\u6599\uff1a<\/strong>
\u7eb3\u7c73\u751f\u7269\u30013D\u6253\u5370\u7b49
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\u690d\u7269\uff1a<\/strong>\u6d66\u80af\u91ce\u7ea4\u7ef4\u7b49<\/p>\n<\/div>\n\n\n\n

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\"\"<\/figure>\n<\/div>\n<\/div>\n\n\n\n

Lumaquant\u56fe\u50cf\u5206\u6790\u8f6f\u4ef6<\/strong><\/p>\n\n\n\n

\u4e13\u4e1a\u5206\u6790\u8f6f\u4ef6\u5185\u7f6e\u591a\u79cd\u5e94\u7528\uff0c\u5305\u542b\u7ec6\u80de\u589e\u6b96\u6a21\u5757\uff0c\u7ec6\u80de\u51cb\u4ea1\u6a21\u5757\uff0c\u7ec6\u80de\u8fc1\u79fb\u6a21\u5757\uff0c\u7ec6\u80de\u8ffd\u8e2a\u6a21\u5757\uff0c\u6838\u8ffd\u8e2a\u6a21\u5757\uff0c\u7ec6\u80de\u8f6c\u67d3\u6a21\u5757\uff0c\u795e\u7ecf\u8f74\u7a81\u751f\u957f\u6a21\u5757\uff0c\u9897\u7c92\u8ffd\u8e2a\u6a21\u5757\uff0c\u5355\u514b\u9686\u5206\u6790\u6a21\u5757\uff0c\u5fc3\u808c\/\u9499\u79bb\u5b50\u6d41\u6a21\u5757\u7b49\uff0c\u7b80\u5355\u5feb\u901f\u83b7\u53d6\u6570\u636e\uff1a\u6279\u91cf\u7f16\u8f91\u56fe\u7247\u3001\u89c6\u9891\uff0c\u4e00\u952e\u5bfc\u51fa\u4fdd\u5b58\uff1b\u6279\u91cf\u5904\u7406\u5b9e\u9a8c\u6587\u4ef6\uff0c\u81ea\u52a8\u5bf9\u5355\u7ec6\u80de\u53ca\u7fa4\u4f53\u7ec6\u80de\u8fdb\u884c\u5b9a\u91cf\u7edf\u8ba1\uff0c\u63d0\u4f9b\u5f62\u6001\u5b66\u548c\u884c\u4e3a\u5b66\u53c2\u6570\uff0c\u5305\u62ec\u6570\u91cf\uff0c\u5706\u5ea6\uff0c\u9762\u79ef\uff0c\u5468\u957f\uff0c\u8367\u5149\u5f3a\u5ea6\uff0c\u901f\u5ea6\uff0c\u52a0\u901f\u5ea6\u7b49\uff0c\u6570\u636e\u53ef\u4e00\u952e\u5bfc\u51fa\u3002<\/p>\n\n\n\n

\u81ea\u52a8\u7ec6\u80de\u8ba1\u6570\u4e0e\u66f2\u7ebf\u62df\u5408<\/strong><\/p>\n\n\n\n

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AI\u667a\u80fd\u5b66\u4e60<\/strong><\/p>\n\n\n\n

\u53ef\u4ee5\u8bbe\u8ba1\u5206\u6790\u8f6f\u4ef6\u6d41\u7a0b\u65b9\u6848\u4ee5\u4fbf\u5feb\u6377\u7684\u533a\u5206\u76ee\u6807\u5bf9\u8c61\u53ca\u80cc\u666f\u3002Pixel classifier\u529f\u80fd\u63d0\u4f9b\u4f20\u7edf\u56fe\u50cf\u5206\u6790\u8f6f\u4ef6\u65e0\u6cd5\u5b9e\u73b0\u7684\u6837\u54c1\u8bc6\u522b\u548c\u68c0\u6d4b\u65b9\u6cd5\u3002<\/p>\n\n\n\n

<\/div>\n\n\n\n

\u7ec6\u80de\u4e9a\u7fa4\u5206\u6790<\/strong><\/p>\n\n\n\n

\u8f6f\u4ef6\u5177\u6709\u5f3a\u5927\u7684\u5206\u5272\u548c\u8ba1\u7b97\u80fd\u529b\uff0c\u901a\u8fc7\u8367\u5149\u6807\u8bb0\u7269\u68c0\u6d4b\uff0c\u53ef\u5b9e\u65f6\u5b9a\u91cf\u68c0\u6d4b\u7ec6\u80de\u4e9a\u7fa4\u7684\u53d8\u5316\u3002<\/p>\n<\/div>\n\n\n\n

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\"\"<\/figure>\n<\/div>\n<\/div>\n\n\n\n

\u5b9e\u7528\u6848\u4f8b<\/strong><\/p>\n\n\n\n

\u7ec6\u80de\u8fc1\u79fb\/\u4fb5\u88ad\/\u8d8b\u5316\u8fd0\u52a8\u2014\u2014transwell<\/strong><\/p>\n\n\n\n

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\"\"
\u4f7f\u7528SiMPore\u516c\u53f8\u8584\u819c\u8fdb\u884ctranswell\u7ec6\u80de\u8d8b\u5316\u8fd0\u52a8\u5b9e\u9a8c\uff0c\u4e24\u56fe\u5206\u522b\u4e3a\u7ec6\u80de\u5728\u819c\u4e0a\u65b9\u7684\u76f8\u5dee\u56fe\u50cf\u53ca\u8f6f\u4ef6\u8ba1\u7b97\u540e\u7684\u4f2a\u5f69\u56fe\u50cf\u3002\u5de6\u56fe\uff1a\u819c\u4e0a\u65b9\uff08\u900f\u660e\u7ec6\u80de\uff09\u548c\u819c\u4e0b\u65b9\uff08\u6697\u8272\u7ec6\u80de\uff09\u7684\u7ec6\u80de\uff1b\u53f3\u56fe\uff1a\u7d2b\u8272\uff08\u819c\u4e0b\u5c42\u900f\u8fc7\u7ec6\u80de\uff09\u548c\u84dd\u8272\uff08\u819c\u4e0a\u5c42\u900f\u660e\u7ec6\u80de\uff09\u662f\u76f8\u5dee\u56fe\u50cf\u7684\u4f2a\u5f69\uff08mask\uff09,\u53d7\u8d8b\u5316\u56e0\u5b50\u4f5c\u7528\uff0c\u819c\u4e0a\u65b9\u7684\u7ec6\u80de\u9010\u6e10\u51cf\u5c11\u3002<\/figcaption><\/figure>\n\n\n\n

\u7ec6\u80de\u5468\u671f\u68c0\u6d4b<\/strong><\/p>\n\n\n\n

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\n
\"\"<\/figure>\n<\/figure>\n\n\n\n

\u5355\u7ec6\u80de\u8fd0\u52a8\u8ffd\u8e2a<\/strong><\/p>\n\n\n\n

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\"\"<\/figure>\n\n\n\n

3D\u57f9\u517b\u4e0e\u80bf\u7624\u5fae\u73af\u5883<\/strong><\/p>\n\n\n\n

\u80bf\u7624\u5fae\u73af\u5883\uff08tumor microenvironment ,TME\uff09\uff0c\u4e3a\u80bf\u7624\u7ec6\u80de\u751f\u5b58\u573a\u6240\uff0c\u662f\u4e00\u4e2a\u52a8\u6001\u590d\u6742\u7684\u7f51\u7edc\u3002\u5b9e\u4f53\u7624\u7684\u73af\u5883\u4e2d\u5305\u542b\uff1a\u80bf\u7624\u7ec6\u80de\u3001\u80bf\u7624\u5468\u56f4\u548c\u5185\u90e8\u805a\u96c6\u7684\u5927\u91cf\u514d\u75ab\u7ec6\u80de\u3001\u80bf\u7624\u8840\u7ba1\u3001\u5185\u76ae\u7ec6\u80de\u3001\u6210\u7ea4\u7ef4\u7ec6\u80de\u3001\u7ec6\u80de\u5916\u57fa\u8d28\u548c\u95f4\u8d28\u7ec4\u7ec7\u7b49\uff0c\u8fd9\u4e9b\u90fd\u662f\u5f71\u54cd\u80bf\u7624\u8f6c\u79fb\u7684\u5173\u952e\u56e0\u7d20\u3002\u7814\u7a76\u53d1\u73b0\uff0c\u80bf\u7624\u5fae\u73af\u5883\u4e2d\u7684\u591a\u7ec6\u80de\u7ec4\u6210\uff0c\u5f80\u5f80\u4f1a\u51b3\u5b9a\u5bf9\u67d0\u79cd\u7279\u5b9a\u7597\u6cd5\u7684\u5f71\u54cd\uff0c\u8fdb\u800c\u51b3\u5b9a\u764c\u75c7\u6cbb\u7597\u7684\u6210\u8d25\u30023D\u57f9\u517b\u4f53\u7cfb\u5df2\u6210\u4e3a\u4f53\u5916\u7814\u7a76\u590d\u6742\u7cfb\u7edf\uff08\u5982TME\uff09\u7684\u6807\u51c6\uff0c\u53ef\u4ee5\u901a\u8fc7\u8fd9\u4e9b\u4f53\u7cfb\u6df1\u5165\u4e86\u89e3\u4f53\u5185\u53d1\u751f\u7684\u7ec6\u80de-\u7ec6\u80de\u76f8\u4e92\u4f5c\u7528\u548c\u901a\u4fe1\u3002LS720\u7a33\u5b9a\u7684\u79fb\u52a8\u5e73\u53f0\u53ef\u8ddf\u8e2a\u548c\u6d4b\u91cf\u975e\u8d34\u58c1\u7684\u4e09\u7ef4\u80bf\u7624\u7403\u4f53\u7684\u5f62\u6210\u3001\u751f\u957f\u548c\u6536\u7f29,\u76d1\u63a7\u836f\u7269\u6291\u5236\u80bf\u7624\u7403\u4f53\u7684\u60c5\u51b5\uff1a1\uff09\u4f7f\u7528\u4f4e\u6210\u672c\u768496\u6216384\u5b54\u5b9e\u9a8c\u65b9\u6848\uff0c\u64cd\u4f5c\u7b80\u4fbf\uff1b2)\u7cbe\u51c6\u5b9a\u4f4d\uff0c\u65e0\u9700\u4eba\u5de5\u91c7\u96c6\u56fe\u50cf\uff0c\u51cf\u5c11\u5b9e\u9a8c\u91cd\u590d\u6027\uff1b3\uff09\u81ea\u52a8\u5b9a\u91cf\u5206\u6790\u7403\u4f53\u5927\u5c0f\uff0c\u5468\u957f\uff0c\u9762\u79ef\u6216\u8367\u5149\u5f3a\u5ea6\u7b49\u6307\u6807\uff0c\u91cf\u5316\u7403\u4f53\u5065\u5eb7\u72b6\u51b5\u3002<\/p>\n\n\n\n

\"\"
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\u795e\u7ecf\u793a\u8e2a<\/strong><\/p>\n\n\n\n

LS720\u53ef\u81ea\u52a8\u91c7\u96c6\u53ca\u5b9a\u91cf\u5206\u6790\u539f\u4ee3\u795e\u7ecf\u7ec6\u80de\u548c\u591a\u80fd\u8bf1\u5bfc\u5e72\u7ec6\u80de\u6765\u6e90\uff08iPSC-derived\uff09\u7684\u795e\u7ecf\u7ec6\u80de\u7684\u795e\u7ecf\u7a81\u7684\u751f\u957f\u72b6\u51b5:1\uff09\u8f6f\u4ef6\u81ea\u52a8\u5c55\u793a\u5e76\u6d4b\u91cf\u795e\u7ecf\u5143\u7684\u6811\u7a81\uff0c\u8f74\u7a81\u4ee5\u53ca\u5fae\u7ba1\u7ed3\u6784\uff0c2\uff09\u53ef\u81ea\u52a8\u83b7\u5f97\u5206\u652f\u957f\u5ea6\uff0c\u5206\u652f\u70b9\u7b49\u795e\u7ecf\u4e13\u4e1a\u5206\u6790\u53c2\u6570\uff1b3\uff09\u8fd0\u7528Z-stack\u53e0\u5c42\u626b\u63cf\uff0c\u5c06\u201c\u659c\u201d\u5411\u751f\u957f\u795e\u7ecf\u5143\uff08\u5373\u795e\u7ecf\u5143\u6811\u7a81\u5206\u652f\u5c42\u9762\u4e0d\u5728\u5355\u4e00\u7684\u62cd\u6444\u5c42\u9762\uff09\u7eb5\u5411\u591a\u5c42\u62cd\u6444\uff0c\u5e76\u53ef\u91cd\u53e0\u6574\u5408\u6210Z-max\u6216\u4e09\u7ef4\u91cd\u6784\u56fe\u50cf\uff0c\u6709\u5229\u4e8e\u5206\u6790\u590d\u6742\u7684\u795e\u7ecf\u5143\u7ed3\u6784\u3002<\/p>\n\n\n\n

\"\"
\u795e\u7ecf\u7ec6\u80de\u7a81\u89e6\u53d8\u5316\uff0c0h,34h,200h<\/figcaption><\/figure>\n\n\n\n

\u4e9a\u7ec6\u80de\u5b9a\u4f4d<\/strong><\/p>\n\n\n\n

\u53ef\u8fdb\u884c\u8840\u8111\u5c4f\u969c\u8c03\u8282\u673a\u5236\u7814\u7a76\uff0c\u8bb0\u5f55NHE9\uff08\u6c22\u94a0\u4ea4\u6362\u4f53\uff0c\u4e00\u79cd\u79bb\u5b50\u8f6c\u8fd0\u86cb\u767d\uff09\u5b9a\u4f4d\u4e8e\u4eba\u8111\u5fae\u8840\u7ba1\u5185\u76ae\u7ec6\u80de(hBMVECs)\u4e2d\u518d\u5faa\u73af\u5185\u4f53\uff08\u6838\u5185\u4f53\u7684\u67d0\u9636\u6bb5\uff0c\u771f\u6838\u7ec6\u80de\u4e2d\u7684\u819c\u7ed3\u5408\u7ec6\u80de\u5668\uff0c\u56ca\u6ce1\u7ed3\u6784\uff09\u8fc7\u7a0b\u3002<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

\u90e8\u5206\u53c2\u8003\u6587\u732e\uff1a
1] Del Rio B, Redruello B, et al. (2019)The biogenic amines putrescine and cadaverine show in vitro cytotoxicity at concentrations that can be found in foods,Sci Rep.
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4] Jo YJ, Lee IW, et al.( 2018 ) Spire localization via zinc finger\u2013containing domain is crucial for the asymmetric division of mouse oocyte.FASEB J.
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6] Beatrizdel Rio, Bego\u00f1a Redruello, et al.( 2018 )Spermine and spermidine are cytotoxic towards intestinal cell cultures, but are they a health hazard at concentrations found in foods.
7] Tamaskovic R, Schwill M, et al. (2016) Intermolecular biparatopic trapping of ErbB2 prevents compensatory activation of PI3K\/AKT via RAS-p110 crosstalk. Nature Communications.
8] Lee HS, Seok H, et al.( 2015) Abasic pivot substitution harnesses target specificity of RNA interference.Nature Communications.
9] Reid JA, Mollica PA,et al. (2016)Accessible bioprinting: adaptation of a low-cost 3D-printer for precise cell placement and stem cell differentiation.Biofabrication.
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11] Miotto M, Gouveia R, et al.( 2017)Developing a Continuous Bioprocessing Approach to Stromal Cell Manufacture. ACS Appl Mater Interfaces.
12] Lee IW, Jo YJ, et al.( 2017)Distinct roles of Cep192 and Cep152 in acentriolar MTOCs and spindle formation during mouse oocyte maturation. FASEB J.
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16] Ghaemi R, Rezai P,et al. (2015)Microfluidic devices for imaging neurological response of Drosophila melanogaster larva to auditory stimulus.\uff0cLab Chip.
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18] Ricardo M., et al. (2013)Bioactive films produced from self-assembling peptide amphiphiles as versatile substrates for tuning cell adhesion and tissue architecture in serum-free conditions. J. Mater. Chem.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

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